R.J. Knox

Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954

John Bridgewater, Caroline J. Springer, R.J. Knox et al. · European Journal of Cancer · 1995 · 209 citations

Biochemistry, Prodrug Cb1954, Medicine +10

The Bystander Effect of the Nitroreductase/CB 1954 Enzyme/Prodrug System Is Due to a Cell-Permeable Metabolite

John Bridgewater, R.J. Knox, J. D. Pitts et al. · Human Gene Therapy · 1997 · 140 citations

Bioactivation of dinitrobenzamide mustards by an E. coli B nitroreductase

Gill Anlezark, Roger G. Melton, Roger F. Sherwood et al. · Biochemical Pharmacology · 1995 · 88 citations

Biosynthesis, Bioorganic Chemistry, Engineering +10

Selective cell ablation in transgenic mice expressing E. coli nitroreductase

AJ Clark, M Iwobi, Wei Cui et al. · Gene Therapy · 1997 · 76 citations

Molecular Biotechnology, Engineering, Protein Expression +10

Indirect Determination of Inorganic Phosphate by Atomic Absorption Spectrophotometric Determination of Molybdenum.

W.S. Zaugg, R.J. Knox · Analytical Chemistry · 1966 · 58 citations

Inorganic Chemistry, Chemical Engineering, Engineering +11