Dave M. Ritchie

Tepoxalin: a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile.

Dennis Argentieri, Dave M. Ritchie, Michael P. Ferro et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 133 citations

Medicine, Medicinal Chemistry, Pharmacology +13

1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2

Zhihua Sui, Jihua Guan, Michael P. Ferro et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 76 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Involvement of lipoxygenase products in myometrial contractions

Robert P. Carraher, Robert P. Carraher, D.W. Hahn et al. · Prostaglandins · 1983 · 71 citations

Life Sciences, Biochemistry, Cell Biology +9

Effects of tepoxalin, a dual inhibitor of cyclooxygenase/5-lipoxygenase, on events associated with NSAID-induced gastrointestinal inflammation

Thomas Kirchner, Beatriz L. Aparicio, Dennis Argentieri et al. · Prostaglandins Leukotrienes and Essential Fatty Acids · 1997 · 59 citations

Medicine, Pharmacology, Pharmacotherapy +14

Evaluation of the Antiinflammatory Activity of a Dual Cyclooxygenase-2 Selective/5-Lipoxygenase Inhibitor, RWJ 63556, in a Canine Model of Inflammation

Thomas Kirchner, Dennis Argentieri, Arminda G. Barbone et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 41 citations

Medicine, Pharmacology, Pharmacotherapy +17