Edward H. Leiter

Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity

Jürgen Κ. Naggert, Lloyd D. Fricker, Oleg Varlamov et al. · Nature Genetics · 1995 · 667 citations

Obesity, Metabolic Syndrome, Carboxypeptidase E Mutation +12

The NOD mouse model of type 1 diabetes: As good as it gets?

Mark A. Atkinson, Edward H. Leiter · Nature Medicine · 1999 · 590 citations

Type 1, Translational Medicine, Insulin Management +7

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice.

David Serreze, H.D. Chapman, Don S. Varnum et al. · The Journal of Experimental Medicine · 1996 · 584 citations · Full text

Null Mice, Lymphocyte Development, Immunology +19

Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.

Micha J. Rapoport, Andrés Jaramillo, Danny Zipris et al. · The Journal of Experimental Medicine · 1993 · 505 citations · Full text

B Lymphocytes Are Critical Antigen-Presenting Cells for the Initiation of T Cell-Mediated Autoimmune Diabetes in Nonobese Diabetic Mice

David Serreze, Sara Fleming, Harold D. Chapman et al. · The Journal of Immunology · 1998 · 454 citations

Immunological Memory, Immunogenetics, Autoimmune Disease +13