Thomas Fischer

Rap1b is required for normal platelet function and hemostasis in mice

Magdalena Chrzanowska‐Wodnicka, Susan S. Smyth, Simone M. Schoenwaelder et al. · Journal of Clinical Investigation · 2005 · 307 citations · Full text

Medicine, Hematology, Molecular Biology +17

Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke

Jens Neumann, Monika Riek‐Burchardt, Josephine Herz et al. · Acta Neuropathologica · 2014 · 275 citations

Life Sciences, Immunology, Neuroscience +17

Phase IB study of the FLT3 kinase inhibitor midostaurin with chemotherapy in younger newly diagnosed adult patients with acute myeloid leukemia

Richard M. Stone, Thomas Fischer, Ron Paquette et al. · Leukemia · 2012 · 273 citations · Full text

Medicine, Hematology, Oncology +13

Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome

Sabine Käyser, Richard F. Schlenk, Martina Correa Londoño et al. · Blood · 2009 · 269 citations · Full text

Medicine, Genetics, Oncology +14

Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain

Florian H. Heidel, Fian K. Solem, Frank Breitenbuecher et al. · Blood · 2005 · 268 citations

Medicine, Oncology, Pharmacology +17