Frank Breitenbuecher

Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome

Sabine Käyser, Richard F. Schlenk, Martina Correa Londoño et al. · Blood · 2009 · 269 citations · Full text

Medicine, Genetics, Oncology +14

Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain

Florian H. Heidel, Fian K. Solem, Frank Breitenbuecher et al. · Blood · 2005 · 268 citations

Medicine, Oncology, Pharmacology +17

Inactivation of Capicua drives cancer metastasis

Ross A. Okimoto, Frank Breitenbuecher, Victor Olivas et al. · Nature Genetics · 2016 · 167 citations

Medicine, Cancer Biology, Oncology +12

Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor

Frank Breitenbuecher, Susanne Schnittger, Rebekka Grundler et al. · Blood · 2008 · 142 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Efficacy and safety of imatinib in adult patients with c-kit–positive acute myeloid leukemia

Thomas Kindler, Frank Breitenbuecher, Andreas Marx et al. · Blood · 2004 · 135 citations · Full text

Medicine, Hematology, Oncology +6