Timothy J. Blackburn

Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein−Protein Interaction: Structure−Activity Studies Leading to Improved Potency

Ian R. Hardcastle, Junfeng Liu, Eric Valeur et al. · Journal of Medicinal Chemistry · 2011 · 149 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Characterisation of a Tip60 Specific Inhibitor, NU9056, in Prostate Cancer

Kelly Coffey, Timothy J. Blackburn, Susan Cook et al. · PLoS ONE · 2012 · 149 citations · Full text

Medicine, Oncology, Pharmacology +11

Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction

Gianni Chessari, Ian R. Hardcastle, Jong Sook Ahn et al. · Journal of Medicinal Chemistry · 2021 · 53 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Pacemaker-induced superior vena cava syndrome: Consideration of management

Timothy J. Blackburn, Marvin Dunn · American Heart Journal · 1988 · 49 citations

Medicine, Cardiology, Surgery +10

Validating and enabling phosphoglycerate dehydrogenase (PHGDH) as a target for fragment-based drug discovery in PHGDH-amplified breast cancer

Judith E. Unterlass, Arnaud Baslé, Timothy J. Blackburn et al. · Oncotarget · 2016 · 38 citations · Full text

Life Sciences, Biochemistry, Oncology +16