Aman Iqbal

Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP

Gianni Chessari, Ildiko M. Buck, James E. H. Day et al. · Journal of Medicinal Chemistry · 2015 · 86 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP)

Emiliano Tamanini, Ildiko M. Buck, Gianni Chessari et al. · Journal of Medicinal Chemistry · 2017 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors

Christopher W. Murray, Valério Berdini, Ildiko M. Buck et al. · ACS Medicinal Chemistry Letters · 2015 · 61 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Studies on Deacetoxycephalosporin C Synthase Support a Consensus Mechanism for 2-Oxoglutarate Dependent Oxygenases

Hanna Tarhonskaya, Andrea Szöllössi, Ivanhoe K. H. Leung et al. · Biochemistry · 2014 · 53 citations

Life Sciences, Biochemistry, Molecular Biology +15

Conformational dynamics of the TTD–PHD histone reader module of the UHRF1 epigenetic regulator reveals multiple histone-binding states, allosteric regulation, and druggability

R. Scott Houliston, Alexander Lemak, Aman Iqbal et al. · Journal of Biological Chemistry · 2017 · 46 citations · Full text

Life Sciences, Genetics, Molecular Biology +14