Ildiko M. Buck

Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Discovery of a Non-Alanine Lead Series with Dual Activity Against cIAP1 and XIAP

Gianni Chessari, Ildiko M. Buck, James E. H. Day et al. · Journal of Medicinal Chemistry · 2015 · 86 citations · Full text

Drug Target, Apoptosis Protein, Apoptosis +17

Discovery of a Potent Nonpeptidomimetic, Small-Molecule Antagonist of Cellular Inhibitor of Apoptosis Protein 1 (cIAP1) and X-Linked Inhibitor of Apoptosis Protein (XIAP)

Emiliano Tamanini, Ildiko M. Buck, Gianni Chessari et al. · Journal of Medicinal Chemistry · 2017 · 70 citations · Full text

Drug Target, Biomolecular Structure Prediction, Apoptosis Protein +21

Design, Synthesis, and Structure−Activity Relationships of Novel Non-Imidazole Histamine H₃ Receptor Antagonists

Ian D. Linney, Ildiko M. Buck, Elaine A. Harper et al. · Journal of Medicinal Chemistry · 2000 · 65 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +14

Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2

Tom D. Heightman, Valério Berdini, Hannah Braithwaite et al. · Journal of Medicinal Chemistry · 2018 · 63 citations · Full text

Multiple Cancers, Tumor Biology, Medicinal Chemistry +22

Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors

Christopher W. Murray, Valério Berdini, Ildiko M. Buck et al. · ACS Medicinal Chemistry Letters · 2015 · 60 citations · Full text

Medicinal Chemistry, Back Pocket, Drug Target +14