Pingda Ren

The translational landscape of mTOR signalling steers cancer initiation and metastasis

Andrew C. Hsieh, Yi Liu, Merritt P. Edlind et al. · Nature · 2012 · 1.4K citations

Medicine, Cancer Biology, Oncology +14

Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor

Matthew R. Janes, Jingchuan Zhang, Lian‐Sheng Li et al. · Cell · 2018 · 1.2K citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +12

Selective Inhibition of Oncogenic KRAS Output with Small Molecules Targeting the Inactive State

Matthew P. Patricelli, Matthew R. Janes, Lian‐Sheng Li et al. · Cancer Discovery · 2016 · 754 citations · Full text

Medicine, Medicinal Chemistry, Oncology +17

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

Matthew R. Janes, Jose J. Limon, Lomon So et al. · Nature Medicine · 2010 · 338 citations · Full text

Medicine, Oncology, Pharmacology +14

The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors

Alex Berndt, Simon Miller, Olusegun Williams et al. · Nature Chemical Biology · 2010 · 292 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15