Alexander D. Lewis

Direct measurement of pO2 distribution and bioreductive enzymes in human malignant brain tumors

R Rampling, Garth Cruickshank, Alexander D. Lewis et al. · International Journal of Radiation Oncology*Biology*Physics · 1994 · 300 citations

Medicine, Neuroscience, Oncology +14

Reductase Enzyme Expression Across the National Cancer Institute Tumor Cell Line Panel: Correlation With Sensitivity to Mitomycin C and EO9

Sara A. Fitzsimmons, Paul Workman, Michael R. Grever et al. · JNCI Journal of the National Cancer Institute · 1996 · 235 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Cellular heterogeneity and drug resistance in two ovarian adenocarcinoma cell lines derived from a single patient

C. Roland Wolf, Ian P. Hayward, S. S. Lawrie et al. · International Journal of Cancer · 1987 · 139 citations

Medicine, Cancer Biology, Oncology +14

Amplification and increased expression of alpha class glutathione S-transferase-encoding genes associated with resistance to nitrogen mustards.

Alexander D. Lewis, Ian D. Hickson, Craig Robson et al. · Proceedings of the National Academy of Sciences · 1988 · 137 citations · Full text

Medicine, Biochemistry, Cancer Biology +13

Reduced levels of drug-induced DNA cross-linking in nitrogen mustard-resistant Chinese hamster ovary cells expressing elevated glutathione S-transferase activity.

Craig Robson, Alexander D. Lewis, C. Roland Wolf et al. · PubMed · 1987 · 111 citations

Medicine, Cancer Biology, Molecular Biology +17