Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis

Jianqiang Mao, Francesco J. DeMayo, Li Huiguang, +7

Proceedings of the National Academy of Sciences

Glucose HomeostasisLiver-specific DeletionFatty Liver DiseaseMetabolic SyndromeLiver-specific Acc1 Knockout +15

Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die <i>in utero</i>

Subrahmanyam S. Chirala, Hua Chang, Martin M. Matzuk, +5

Proceedings of the National Academy of Sciences

GeneticsEmbryologyBiosynthesisGene DosageSynthase Null Mutants +17

Integrated analysis of mRNA-seq and miRNA-seq in the liver of Pelteobagrus vachelli in response to hypoxia

Guosong Zhang, Shaowu Yin, Jianqiang Mao, +6

Scientific Reports

Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE

Franky Van Herreweghe, Jianqiang Mao, Frank Chaplen, +4

Proceedings of the National Academy of Sciences

Specific Methylglyoxal-derived AgeLipid PeroxidationApoptosisImmunologyCell Death +17

ErbB2 Pathway Activation upon Smad4 Loss Promotes Lung Tumor Growth and Metastasis

Jian Liu, Sung-Nam Cho, Bindu Akkanti, +10

Cell Reports

SRC-2 Is an Essential Coactivator for Orchestrating Metabolism and Circadian Rhythm

Erin Stashi, Rainer B. Lanz, Jianqiang Mao, +15

Cell Reports

Modulated expression and enzymatic activities of Darkbarbel catfish, Pelteobagrus vachelli for oxidative stress induced by acute hypoxia and reoxygenation

Guosong Zhang, Jianqiang Mao, Fenfei Liang, +6

Chemosphere

BiologyBiochemistryRedox RegulatorNatural SciencesPhysiology +8

Human acetyl-CoA carboxylase 1 gene: Presence of three promoters and heterogeneity at the 5′-untranslated mRNA region

Jianqiang Mao, Subrahmanyam S. Chirala, Salih J. Wakil

Proceedings of the National Academy of Sciences

Pharmacological inhibition of CaMKK2 with the selective antagonist STO-609 regresses NAFLD

Brian York, Feng Li, Fumin Lin, +9

Scientific Reports

aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues

Jianqiang Mao, Tao Yang, Ziwei Gu, +4

Proceedings of the National Academy of Sciences

Ap2-cre-mediated InactivationMetabolic RemodelingBone TissueOxidative StressObesity +18