Ta-Chun Cheng

Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes

Yuan-Chin Hsieh, Hsin-Ell Wang, Wen-Wei Lin et al. · Theranostics · 2018 · 103 citations · Full text

An Activity-Based Near-Infrared Glucuronide Trapping Probe for Imaging β-Glucuronidase Expression in Deep Tissues

Ta-Chun Cheng, Steve R. Roffler, Shey-Cherng Tzou et al. · Journal of the American Chemical Society · 2012 · 94 citations

Engineering, Nir Glucuronide Probes, Glycobiology +16

Pharmacological inhibition of bacterial β-glucuronidase prevents irinotecan-induced diarrhea without impairing its antitumor efficacy in vivo

Kai-Wen Cheng, Chih-Hua Tseng, Cherng‐Chyi Tzeng et al. · Pharmacological Research · 2018 · 87 citations

Health Sciences, Microbial Pathogens, Gastrointestinal Pharmacology +9

One-step mixing with humanized anti-mPEG bispecific antibody enhances tumor accumulation and therapeutic efficacy of mPEGylated nanoparticles

Chien-Han Kao, Jaw‐Yuan Wang, Kai‐Hsiang Chuang et al. · Biomaterials · 2014 · 59 citations

Nanomedicine, Nanotherapeutics, Mpegylated Nanoparticles +10

Discovery of Akt Kinase Inhibitors through Structure-Based Virtual Screening and Their Evaluation as Potential Anticancer Agents

Chih‐Hung Chuang, Ta-Chun Cheng, Yu-Ling Leu et al. · International Journal of Molecular Sciences · 2015 · 54 citations · Full text

Drug Target, Hit Identification, Chemoprevention Strategy +22