Kai-Wen Cheng

Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus

Kai-Wen Cheng, Shu‐Chun Cheng, Wei‐Yi Chen et al. · Antiviral Research · 2014 · 196 citations

Life Sciences, Infectious Diseases, Pharmacology +17

Pharmacological inhibition of bacterial β-glucuronidase prevents irinotecan-induced diarrhea without impairing its antitumor efficacy in vivo

Kai-Wen Cheng, Chih-Hua Tseng, Cherng‐Chyi Tzeng et al. · Pharmacological Research · 2018 · 92 citations

Medicine, Pharmacology, Pharmacotherapy +10

Neuronal-driven glioma growth requires Gαi1 and Gαi3

Yin Wang, Yuan-Yuan Liu, Min‐Bin Chen et al. · Theranostics · 2021 · 87 citations · Full text

Medicine, Cancer Biology, Oncology +13

Structural basis for catalysis and ubiquitin recognition by the<i>Severe acute respiratory syndrome coronavirus</i>papain-like protease

Chi‐Yuan Chou, Hsing-Yi Lai, Hung-Yi Chen et al. · Acta Crystallographica Section D Biological Crystallography · 2014 · 61 citations · Full text

Life Sciences, Biology, Molecular Biology +16

Specific Inhibition of Bacterial β-Glucuronidase by Pyrazolo[4,3-<i>c</i>]quinoline Derivatives via a pH-Dependent Manner To Suppress Chemotherapy-Induced Intestinal Toxicity

Kai-Wen Cheng, Chih-Hua Tseng, Chia‐Ning Yang et al. · Journal of Medicinal Chemistry · 2017 · 41 citations

Medicine, Medicinal Chemistry, Pharmacology +15