Takako Okumura

CJ-023,423, a Novel, Potent and Selective Prostaglandin EP4 Receptor Antagonist with Antihyperalgesic Properties

Kazunari Nakao, Akio Murase, Hiroyuki Ohshiro et al. · Journal of Pharmacology and Experimental Therapeutics · 2007 · 120 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Novel imidazole compounds as a new series of potent, orally active inhibitors of 5-lipoxygenase

Takashi Mano, Rodney W. Stevens, Kazuo Ando et al. · Bioorganic & Medicinal Chemistry · 2003 · 57 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

Effect of prostanoid EP4 receptor antagonist, CJ-042,794, in rat models of pain and inflammation

Akio Murase, Takako Okumura, Ayano Sakakibara et al. · European Journal of Pharmacology · 2007 · 57 citations

Life Sciences, Pharmacology, Inflammation +13

4-[5-Fluoro-3-[4-(2-methyl-1<i>H</i>-imidazol-1-yl)benzyloxy]phenyl]-3,4,5,6- tetrahydro-2<i>H</i>-pyran-4-carboxamide, an Orally Active Inhibitor of 5-Lipoxygenase with Improved Pharmacokinetic and Toxicology Characteristics

Takashi Mano, Yoshiyuki Okumura, Minoru Sakakibara et al. · Journal of Medicinal Chemistry · 2003 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Effects of the selective EP4 antagonist, CJ-023,423 on chronic inflammation and bone destruction in rat adjuvant-induced arthritis

Takako Okumura, Yoko Murata, Kana Taniguchi et al. · Journal of Pharmacy and Pharmacology · 2008 · 30 citations · Full text

Medicine, Pathobiology, Pharmacology +17