Yoshihiko Yagi

Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant:  Lead Identification and SAR of 3- and 4-Substituted Derivatives

Michaël Génin, Carolyn Biles, Barb J. Keiser et al. · Journal of Medicinal Chemistry · 2000 · 378 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pyrimidine Thioethers:  A Novel Class of HIV-1 Reverse Transcriptase Inhibitors with Activity Against BHAP-Resistant HIV

Richard A. Nugent, Stephen T. Schlachter, Michael J. Murphy et al. · Journal of Medicinal Chemistry · 1998 · 68 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Plasmid-determined tetracycline resistance in Streptococcus faecalis: Tandemly repeated resistance determinants in amplified forms of pAMα1 DNA

Yoshihiko Yagi, Don B. Clewell · Journal of Molecular Biology · 1976 · 60 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Targeting Delavirdine/Atevirdine Resistant HIV-1:  Identification of (Alkylamino)piperidine-Containing Bis(heteroaryl)piperazines as Broad Spectrum HIV-1 Reverse Transcriptase Inhibitors

Donna L. Romero, Robert A. Olmsted, Toni J. Poel et al. · Journal of Medicinal Chemistry · 1996 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

(−)-6-Chloro-2-[(1-furo[2,3-<i>c</i>]pyridin-5-ylethyl)thio]-4-pyrimidinamine, PNU-142721, a New Broad Spectrum HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor

Donn G. Wishka, David R. Graber, Laurice A. Kopta et al. · Journal of Medicinal Chemistry · 1998 · 49 citations · Full text

Medicine, Pharmacology, Drug Discovery +8