David P. Davis

Diverse somatic mutation patterns and pathway alterations in human cancers

Zhengyan Kan, Bijay S. Jaiswal, Jeremy Stinson et al. · Nature · 2010 · 1K citations

Medicine, Genetics, Oncology +16

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

Michael Degtyarev, Ann De Mazière, Christine Orr et al. · The Journal of Cell Biology · 2008 · 410 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Oncogenic BRAF Is Required for Tumor Growth and Maintenance in Melanoma Models

Klaus P. Hoeflich, Daniel C. Gray, Michael Eby et al. · Cancer Research · 2006 · 232 citations

Medicine, Medicinal Chemistry, Oncology +14

Maternal Embryonic Leucine Zipper Kinase/Murine Protein Serine-Threonine Kinase 38 Is a Promising Therapeutic Target for Multiple Cancers

Daniel C. Gray, Adrian M. Jubb, Deborah Hogue et al. · Cancer Research · 2005 · 203 citations · Full text

Medicine, Molecular Biology, Oncology +17

Combined Targeting of BRAF and CRAF or BRAF and PI3K Effector Pathways Is Required for Efficacy in NRAS Mutant Tumors

Bijay S. Jaiswal, Vasantharajan Janakiraman, Noelyn M. Kljavin et al. · PLoS ONE · 2009 · 108 citations · Full text

Medicine, Molecular Biology, Oncology +17