Laurence J. Nummy

Development of a concise, scalable synthesis of a CCR1 antagonist utilizing a continuous flow Curtius rearrangement

Maurice A. Marsini, Frédéric G. Buono, Jon C. Lorenz et al. · Green Chemistry · 2017 · 42 citations

Combinatorial Chemistry, Robust Synthesis, Ccr1 Antagonist +10

Formation of 2-Trifluoromethylphenyl Grignard Reagent via Magnesium−Halogen Exchange: Process Safety Evaluation and Concentration Effect

Wenjun Tang, Max Sarvestani, Xudong Wei et al. · Organic Process Research & Development · 2009 · 31 citations

An improved synthesis of N-aryl-hydantoin LFA-1 antagonists via the enantiospecific alkylation of an isobutyraldehyde-derived imidazolidinone template

Rogelio P. Frutos, Sandra Stehle, Laurence J. Nummy et al. · Tetrahedron Asymmetry · 2001 · 30 citations

Combinatorial Chemistry, Medicinal Chemistry, Enantioselective Synthesis +10

Practical Synthesis of an Enantiomerically Pure <i>trans-</i>4,5-Disubstituted 2-Pyrrolidinone via Enzymatic Resolution. Preparation of the LTB₄ Inhibitor BIRZ-227

Nathan K. Yee, Laurence J. Nummy, Denis Byrne et al. · The Journal of Organic Chemistry · 1998 · 26 citations

Medicinal Chemistry, Practical Synthesis, Pharmaceutical Chemistry +15

Practical synthesis of a cell adhesion inhibitor by self-regeneration of stereocenters

Nathan K. Yee, Laurence J. Nummy, Rogelio P. Frutos et al. · Tetrahedron Asymmetry · 2003 · 23 citations

Tissue Engineering, Practical Synthesis, Cell Adhesion Inhibitor +12