Denis Byrne

Efficient Synthesis of Empagliflozin, an Inhibitor of SGLT-2, Utilizing an AlCl₃-Promoted Silane Reduction of a β-Glycopyranoside

Xiao‐jun Wang, Li Zhang, Denis Byrne et al. · Organic Letters · 2014 · 106 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Zinc Catalyzed and Mediated Asymmetric Propargylation of Trifluoromethyl Ketones with a Propargyl Boronate

Daniel R. Fandrick, Jonathan T. Reeves, Johanna M. Bakonyi et al. · The Journal of Organic Chemistry · 2013 · 50 citations

Pharmacy, Chemistry, Medicinal Chemistry +13

Development of a Large Scale Asymmetric Synthesis of the Glucocorticoid Agonist BI 653048 BS H₃PO₄

Jonathan T. Reeves, Daniel R. Fandrick, Zhulin Tan et al. · The Journal of Organic Chemistry · 2013 · 41 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Formation of 2-Trifluoromethylphenyl Grignard Reagent via Magnesium−Halogen Exchange: Process Safety Evaluation and Concentration Effect

Wenjun Tang, Max Sarvestani, Xudong Wei et al. · Organic Process Research & Development · 2009 · 33 citations

Natural Sciences, Chemical Engineering, Chemistry +16

Practical Synthesis of an Enantiomerically Pure <i>trans-</i>4,5-Disubstituted 2-Pyrrolidinone via Enzymatic Resolution. Preparation of the LTB₄ Inhibitor BIRZ-227

Nathan K. Yee, Laurence J. Nummy, Denis Byrne et al. · The Journal of Organic Chemistry · 1998 · 26 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13