Jeffrey S. Culp

Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia

David Cunningham, Dennis E. Danley, Kieran F. Geoghegan et al. · Nature Structural & Molecular Biology · 2007 · 434 citations

Familial Hypercholesterolemia, Molecular Physiology, Biochemistry +10

Immunohistochemical localization of PDE10A in the rat brain

Thomas Seeger, Brenda L. Bartlett, Timothy Coskran et al. · Brain Research · 2003 · 340 citations

Immunohistochemical Localization, Neurophysiology, Neuroanatomy +6

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules

Xiayang Qiu, Anil Mistry, Mark Ammirati et al. · Nature Structural & Molecular Biology · 2007 · 270 citations

Crystal Structure, Proteinlipid Interaction, Long Tunnel +7

Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay

J. Perry Hall, Amy Brault, Fabien Vincent et al. · PLoS ONE · 2017 · 157 citations · Full text

Unique fold and active site in cytomegalovirus protease

Xiayang Qiu, Jeffrey S. Culp, Anthony G. DiLella et al. · Nature · 1996 · 148 citations

Virus Structure, Viral Replication, Protein Folding +8