F. Van Leuven

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper, Paul Säftig, Katleen Craessaerts et al. · Nature · 1998 · 1.8K citations

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Biology +9

Amyloid Activates GSK-3β to Aggravate Neuronal Tauopathy in Bigenic Mice

Dick Terwel, David Muyllaert, Ilse Dewachter et al. · American Journal Of Pathology · 2008 · 286 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Degenerative Disease +9

Changed Conformation of Mutant Tau-P301L Underlies the Moribund Tauopathy, Absent in Progressive, Nonlethal Axonopathy of Tau-4R/2N Transgenic Mice

Dick Terwel, Reena Lasrado, J. Snauwaert et al. · Journal of Biological Chemistry · 2004 · 266 citations · Full text

Prominent Cerebral Amyloid Angiopathy in Transgenic Mice Overexpressing the London Mutant of Human APP in Neurons

Jo Van Dorpe, Liesbet Smeijers, Ilse Dewachter et al. · American Journal Of Pathology · 2000 · 229 citations · Full text

London Mutant, Neurodegenerative Diseases, Alzheimer's Disease +10

Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines.

F. Van Leuven, J.J. Cassiman, Herman Van den Berghe · Journal of Biological Chemistry · 1979 · 227 citations · Full text

Alpha2-macroglobulin Receptor, Immunology, Cellular Pharmacology +24