Lihong Shi

Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

Lihong Shi, Shuaiying Cui, James Douglas Engel et al. · Nature Medicine · 2013 · 169 citations

Life Sciences, Molecular Biology, Pharmacology +12

Nuclear Receptors TR2 and TR4 Recruit Multiple Epigenetic Transcriptional Corepressors That Associate Specifically with the Embryonic β-Type Globin Promoters in Differentiated Adult Erythroid Cells

Shuaiying Cui, Katarzyna E. Kolodziej, Naoshi Obara et al. · Molecular and Cellular Biology · 2011 · 111 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The LSD1 inhibitor RN-1 induces fetal hemoglobin synthesis and reduces disease pathology in sickle cell mice

Shuaiying Cui, Kim-Chew Lim, Lihong Shi et al. · Blood · 2015 · 95 citations · Full text

Medicine, Hematology, Molecular Genetics +8

A Genetic Variant Ameliorates β-Thalassemia Severity by Epigenetic-Mediated Elevation of Human Fetal Hemoglobin Expression

Diyu Chen, Yangjin Zuo, Xinhua Zhang et al. · The American Journal of Human Genetics · 2017 · 43 citations · Full text

Medicine, Genetics, Molecular Genetics +10

Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes

Andrew Campbell, Shuaiying Cui, Lihong Shi et al. · Proceedings of the National Academy of Sciences · 2011 · 41 citations · Full text

Life Sciences, Genetics, Hematology +17