Concepedia

Dennis Bigg

DB

36

Publications

1.5K

Citations

21

H-Index

1991

Active since

Affiliations

Ipsen (France)(Current)

Pierre Fabre (France)

Centre National de la Recherche Scientifique

Laboratoire de Chimie de Coordination

Inserm

Dennis Bigg is an author at Ipsen (France) specializing in pharmacology, medicine, and drug discovery.

Top concepts

Publications per year

1991–2008

36

Publications

36

Homocamptothecins:  Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues

Olivier Lavergne, Laurence Lesueur‐Ginot, Francesc Pla Rodas et al. · Journal of Medicinal Chemistry · 1998 · 150 citations

, , +17

BN 80933, a dual inhibitor of neuronal nitric oxide synthase and lipid peroxidation: A promising neuroprotective strategy

Pierre‐Etienne Chabrier, Michel Auguet, B. Spinnewyn et al. · Proceedings of the National Academy of Sciences · 1999 · 126 citations

, , +20

Aluminum Chloride-Promoted Transamidation Reactions

Eric Bon, Dennis Bigg, Guy Bertrand · The Journal of Organic Chemistry · 1994 · 124 citations

, , +16

BN 80245: An E-ring modified camptothecin with potent antiproliferative and topoisomerase I inhibitory activities

Olivier Lavergne, Laurence Lesueur‐Ginot, Francesc Pla Rodas et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 97 citations

, , +7

Topoisomerase I-Mediated Antiproliferative Activity of Enantiomerically Pure Fluorinated Homocamptothecins

Olivier Lavergne, Danièle Demarquay, Christian Bailly et al. · Journal of Medicinal Chemistry · 2000 · 70 citations

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