Laurence Lesueur‐Ginot

Author

Also Known As

L Lesueur-Ginot, L. LESUEUR‐GINOT, L. Lesueur-Ginot, LAURENCE LESUEUR‐GINOT, Laurence Lesueur-Ginot, Laurence Lesueur‐Ginot

Publications

1.7K

Citations

H-Index

Concepts

All Affiliations

Ipsen (France)

About

Laurence Lesueur‐Ginot is an author at Ipsen (France) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	1.7K
2	Natural Sciences	4	4	231
3	Health Sciences	1	1	97
4	Public Health	1	1	1.1K
5	Biochemistry	1	1	150

Laurence Lesueur‐Ginot

Publications

1.7K

Citations

H-Index

Page 1

	Year	Citations
Genetic associations with human longevity at the APOE and ACE loci François Schächter, Laurence Faure-Delanef, Frédérique Guénot, Nature Genetics BiologyGenetic AssociationsLifespan ExtensionAgingLongevity	1994	1.1K
Homocamptothecins: Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues Olivier Lavergne, Laurence Lesueur‐Ginot, Francesc Pla Rodas, Journal of Medicinal Chemistry Antitumor ActivityChemoprevention StrategyTumor Growth DelayHeterocycle ChemistryPharmaceutical Chemistry	1998	150
Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties. Laurence Lesueur‐Ginot, Danièle Demarquay, Róbert Kiss, PubMed Chemoprevention StrategyCpt AnaloguesCell DeathE-ring Modified CamptothecinToxicological Mechanism	1999	109
BN 80245: An E-ring modified camptothecin with potent antiproliferative and topoisomerase I inhibitory activities Olivier Lavergne, Laurence Lesueur‐Ginot, Francesc Pla Rodas, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryHealth SciencesMedicineE-ring Modified CamptothecinAnti-cancer Agent	1997	97
BN 80927: A novel homocamptothecin with inhibitory activities on both topoisomerase I and topoisomerase II Olivier Lavergne, Jeremiah J. Harnett, Alain Rolland, Bioorganic & Medicinal Chemistry Letters MedicineNatural SciencesMolecular BiologyChemical BiologyPharmacology	1999	54
Homocamptothecin, an E-ring-modified camptothecin, exerts more potent antiproliferative activity than other topoisomerase I inhibitors in human colon cancers obtained from surgery and maintained in vitro under histotypical culture conditions. P. Philippart, Luke Harper, Carole Chaboteaux, PubMed Potent Antiproliferative ActivitySurgical OncologyOncologyGastrointestinal OncologyMedicine	2000	44
Unusual potency of BN 80915, a novel fluorinated E-ring modified camptothecin, toward human colon carcinoma cells. Annette K. Larsen, Cristèele Gilbert, Ginette Chyzak, PubMed Bn 80915Tumor BiologyChemoprevention StrategyGastrointestinal OncologyMedicine	2001	41
BN80927 Danièle Demarquay, Marion Huchet, Hélène Coulomb, Cancer Research Reductive StressDna RelaxationCell RegulationMolecular BiologyCell Death	2004	39
The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison Danièle Demarquay, Marion Huchet, Hélène Coulomb, Anti-Cancer Drugs	2001	34
The Homocamptothecin, BN 80927, Is a Potent Topoisomerase I Poison and Topoisomerase II Catalytic Inhibitor Danièle Demarquay, Hélène Coulomb, Marion Huchet, Annals of the New York Academy of Sciences Medicinal ChemistryNatural SciencesMedicineBn 80927Molecular Biology	2000	14

Page 1