Concepedia

Olivier Lavergne

OL

22

Publications

1.1K

Citations

19

H-Index

1989

Active since

Affiliations

Ipsen (France)(Current)

Laboratoire de Biologie Cellulaire et Moléculaire du Contrôle de la Prolifération

Centre National de la Recherche Scientifique

Université Toulouse III - Paul Sabatier

Inserm

Olivier Lavergne is an author at Ipsen (France) specializing in drug discovery, medicine, and pharmacology.

ORCID

Top concepts

Publications per year

1989–2009

22

Publications

22

Homocamptothecins:  Synthesis and Antitumor Activity of Novel E-Ring-Modified Camptothecin Analogues

Olivier Lavergne, Laurence Lesueur‐Ginot, Francesc Pla Rodas et al. · Journal of Medicinal Chemistry · 1998 · 150 citations

, , +17

Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.

Laurence Lesueur‐Ginot, Danièle Demarquay, Róbert Kiss et al. · PubMed · 1999 · 109 citations

, , +16

BN 80245: An E-ring modified camptothecin with potent antiproliferative and topoisomerase I inhibitory activities

Olivier Lavergne, Laurence Lesueur‐Ginot, Francesc Pla Rodas et al. · Bioorganic & Medicinal Chemistry Letters · 1997 · 97 citations

, , +7

Inhibition of Heterotrimeric G Protein Signaling by a Small Molecule Acting on Gα Subunit

Mohammed Akli Ayoub, Marjorie Damian, Christian Gespach et al. · Journal of Biological Chemistry · 2009 · 75 citations · Full text

, , +20

Topoisomerase I-Mediated Antiproliferative Activity of Enantiomerically Pure Fluorinated Homocamptothecins

Olivier Lavergne, Danièle Demarquay, Christian Bailly et al. · Journal of Medicinal Chemistry · 2000 · 70 citations

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