Jielin Xu

TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis

Jinchao Hou, Jue Zhang, Ping Cui et al. · Journal of Clinical Investigation · 2021 · 218 citations · Full text

Immunology, Pathology, Cell Death +25

Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment

Yadi Zhou, Jielin Xu, Yuan Hou et al. · Alzheimer s Research & Therapy · 2021 · 155 citations · Full text

Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease

Jiansong Fang, Pengyue Zhang, Quan Wang et al. · Alzheimer s Research & Therapy · 2022 · 107 citations · Full text

Graph embedding and Gaussian mixture variational autoencoder network for end-to-end analysis of single-cell RNA sequencing data

Junlin Xu, Jielin Xu, Yajie Meng et al. · Cell Reports Methods · 2023 · 92 citations · Full text

Engineering, Machine Learning, Autoencoders +19

Interpretable deep learning translation of GWAS and multi-omics findings to identify pathobiology and drug repurposing in Alzheimer’s disease

Jielin Xu, Chengsheng Mao, Yuan Hou et al. · Cell Reports · 2022 · 89 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +10