J. D. Burton

The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.

Richard N. Bamford, Angus Grant, J. D. Burton et al. · Proceedings of the National Academy of Sciences · 1994 · 414 citations

Life Sciences, Cell Biology, Immunology +13

A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells.

J. D. Burton, Richard N. Bamford, Christian Peters et al. · Proceedings of the National Academy of Sciences · 1994 · 402 citations

Life Sciences, Immunology, Oncology +12

Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I region /IL-15 fusion message that lacks many upstream AUGs that normally attenuates IL-15 mRNA translation.

Richard N. Bamford, A P Battiata, J. D. Burton et al. · Proceedings of the National Academy of Sciences · 1996 · 234 citations

Life Sciences, Cell Biology, Immunology +9

Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia.

S J Kim, John H. Kehrl, J. D. Burton et al. · The Journal of Experimental Medicine · 1990 · 226 citations · Full text

Life Sciences, Molecular Biology, Oncology +11

Celecoxib exhibits the greatest potency amongst cyclooxygenase (COX) inhibitors for growth inhibition of COX-2-negative hematopoietic and epithelial cell lines.

Chris Waskewich, Rosalyn D. Blumenthal, Honglan Li et al. · PubMed · 2002 · 203 citations

Medicine, Oncology, Pharmacology +13