Qiu Xie

Discovery of Sodium <i>R</i>-(+)-4-{2-[5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2<i>H</i>-pyrimidin-1-yl]-1-phenylethylamino}butyrate (Elagolix), a Potent and Orally Available Nonpeptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor

Chen Chen, Dongpei Wu, Zhiqiang Guo et al. · Journal of Medicinal Chemistry · 2008 · 119 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Novel Blood Biomarkers of Pancreatic Cancer–Associated Diabetes Mellitus Identified by Peripheral Blood–Based Gene Expression Profiles

Hai Huang, Xin Dong, Mu Xing Kang et al. · The American Journal of Gastroenterology · 2010 · 111 citations

Medicine, Molecular Medicine, Oncology +17

Discovery of a Series of Nonpeptide Small Molecules That Inhibit the Binding of Insulin-like Growth Factor (IGF) to IGF-Binding Proteins

Chen Chen, Yunfei Zhu, Xin-Jun Liu et al. · Journal of Medicinal Chemistry · 2001 · 75 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

3-[(2<i>R</i>)-Amino-2-phenylethyl]-1-(2,6-difluorobenzyl)-5-(2-fluoro-3-methoxyphenyl)- 6-methylpyrimidin-2,4-dione (NBI 42902) as a Potent and Orally Active Antagonist of the Human Gonadotropin-Releasing Hormone Receptor. Design, Synthesis, and in Vitro and in Vivo Characterization

Fábio C. Tucci, Yunfei Zhu, R. Scott Struthers et al. · Journal of Medicinal Chemistry · 2005 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Beneficial effect of corticosteroids for patients with severe drug‐induced liver injury

Ping Fang Hu, Pei Qin Wang, Han Chen et al. · Journal of Digestive Diseases · 2016 · 51 citations

Pharmacy, Pharmacology, Pharmacotherapy +13