R. Scott Struthers

Differential Desensitization, Receptor Phosphorylation, β-Arrestin Recruitment, and ERK1/2 Activation by the Two Endogenous Ligands for the CC Chemokine Receptor 7

Trudy A. Kohout, Shelby Nicholas, Stephen J. Perry et al. · Journal of Biological Chemistry · 2004 · 324 citations · Full text

Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant

R. Scott Struthers, Wylie Vale, Carlos Arias et al. · Nature · 1991 · 306 citations

Knockout Mouse, Developmental Biology, Somatic Variant +8

Suppression of Gonadotropins and Estradiol in Premenopausal Women by Oral Administration of the Nonpeptide Gonadotropin-Releasing Hormone Antagonist Elagolix

R. Scott Struthers, Andrew Nicholls, John S. Grundy et al. · The Journal of Clinical Endocrinology & Metabolism · 2008 · 121 citations · Full text

Discovery of Sodium <i>R</i>-(+)-4-{2-[5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2<i>H</i>-pyrimidin-1-yl]-1-phenylethylamino}butyrate (Elagolix), a Potent and Orally Available Nonpeptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor

Chen Chen, Dongpei Wu, Zhiqiang Guo et al. · Journal of Medicinal Chemistry · 2008 · 117 citations · Full text

Novel Uracil Phenylethylamines, Gynecology, Pharmacotherapy +16

Distinct Conformations of the Corticotropin Releasing Factor Type 1 Receptor Adopted following Agonist and Antagonist Binding Are Differentially Regulated

Stephen J. Perry, Sachiko Junger, Trudy A. Kohout et al. · Journal of Biological Chemistry · 2005 · 60 citations · Full text