R. Michael Snider

A Potent Nonpeptide Antagonist of the Substance P (NK ₁ ) Receptor

R. Michael Snider, Jay W. Constantine, John Lowe et al. · Science · 1991 · 864 citations

Medicine, Medicinal Chemistry, Pharmacology +14

CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin.

C Pothoulakis, Ignazio Castagliuolo, J. Thomas LaMont et al. · Proceedings of the National Academy of Sciences · 1994 · 277 citations

Life Sciences, Immunology, Pharmacology +17

Pharmacology of CP-99,994; a nonpeptide antagonist of the tachykinin neurokinin-1 receptor.

Stafford McLean, Alan H. Ganong, P A Seymour et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 222 citations

Medicine, Neuroscience, Pharmacology +11

Discovery of a potent substance P antagonist: recognition of the key molecular determinant

Manoj C. Desai, Sheri L. Lefkowitz, Peter F. Thadeio et al. · Journal of Medicinal Chemistry · 1992 · 220 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Different binding epitopes on the NK1 receptor for substance P and a non-peptide antagonist

Ulrik Gether, Teit E. Johansen, R. Michael Snider et al. · Nature · 1993 · 218 citations

Medicine, Immunology, Pharmacology +13