Clostridium difficile toxin A perturbs cytoskeletal structure and tight junction permeability of cultured human intestinal epithelial monolayers.

Gail Hecht, C Pothoulakis, J. Thomas LaMont, +1

Journal of Clinical Investigation

CP-96,345, a substance P antagonist, inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin.

C Pothoulakis, Ignazio Castagliuolo, J. Thomas LaMont, +4

Proceedings of the National Academy of Sciences

Intravenous immunoglobulin therapy for severe <i>Clostridium difficile</i> colitis

José R. Salcedo, Sarah Keates, C Pothoulakis, +4

Gut

Microbial ToxinIntravenous Immunoglobulin TherapyImmunoglobulin PreparationsAntibioticsMicrobial Pathogens +12

Neutrophil recruitment in Clostridium difficile toxin A enteritis in the rabbit.

Ciarán P. Kelly, Sarah Becker, J Linevsky, +5

Journal of Clinical Investigation

Microbial PathogensImmunologyNeutrophil InfiltrationVeterinary MicrobiologyPertussis Toxin +14

Clostridium difficile toxin A stimulates intracellular calcium release and chemotactic response in human granulocytes.

C Pothoulakis, R Sullivan, David Melnick, +4

Journal of Clinical Investigation

InflammationMicrobial ToxinHuman GranulocytesToxinologyClostridium Difficile +13

Rabbit sucrase-isomaltase contains a functional intestinal receptor for Clostridium difficile toxin A.

C Pothoulakis, Russell Gilbert, Christos Cladaras, +10

Journal of Clinical Investigation

Microbial ToxinToxin ABiochemistryToxin BindingMedicine +12

Purification and properties of Clostridium difficile cytotoxin B.

C Pothoulakis, Lucille M. Barone, Robert Ely, +4

Journal of Biological Chemistry

Characterization of rabbit ileal receptors for Clostridium difficile toxin A. Evidence for a receptor-coupled G protein.

C Pothoulakis, J. Thomas LaMont, R Eglow, +4

Journal of Clinical Investigation

Toxin AImmunotoxicologyImmunologyGastroenterologyCellular Physiology +14

Clostridium difficile toxin A-induced microvascular dysfunction. Role of histamine.

Iwao Kurose, C Pothoulakis, J. Thomas LaMont, +5

Journal of Clinical Investigation

InflammationMicrobial ToxinToxinologyMicrobial PathogensMucosal Immunology +11

Urocortin II mediates pro-inflammatory effects in human colonocytes via corticotropin-releasing hormone receptor 2α

Alan C. Moss, Pauline M. Anton, Tor Savidge, +8

Gut