Manoj C. Desai

A Potent Nonpeptide Antagonist of the Substance P (NK ₁ ) Receptor

R. Michael Snider, Jay W. Constantine, John Lowe et al. · Science · 1991 · 864 citations

Potent Nonpeptide Antagonist, Biochemistry, Functional Selectivity +12

Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection

John O. Link, James G. Taylor, Lianhong Xu et al. · Journal of Medicinal Chemistry · 2013 · 290 citations

Pharmacology of CP-99,994; a nonpeptide antagonist of the tachykinin neurokinin-1 receptor.

Stafford McLean, Alan H. Ganong, P A Seymour et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 222 citations

Discovery of a potent substance P antagonist: recognition of the key molecular determinant

Manoj C. Desai, Sheri L. Lefkowitz, Peter F. Thadeio et al. · Journal of Medicinal Chemistry · 1992 · 220 citations · Full text

Pharmaceutical Science, Drug Target, Altmetric Attention Score +21

Cobicistat (GS-9350): A Potent and Selective Inhibitor of Human CYP3A as a Novel Pharmacoenhancer

Lianhong Xu, Hongtao Liu, Bernard P. Murray et al. · ACS Medicinal Chemistry Letters · 2010 · 200 citations

Human Cyp3a, Pharmacotherapy, Antiviral Drug +19