Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR

Nicole Meisner‐Kober, Martin Hintersteiner, Kurt Mueller, +12

Nature Chemical Biology

Mechanistic CharacterizationMedicinal ChemistryDrug TargetMedicineRational Drug Design +2

Single Bead Labeling Method for Combining Confocal Fluorescence On-Bead Screening and Solution Validation of Tagged One-Bead One-Compound Libraries

Martin Hintersteiner, Thierry Kimmerlin, Frank Kalthoff, +8

Chemistry & Biology

EngineeringSolution ValidationBioanalysisMolecular BiologySingle-molecule Detection +7

Identification of a Small Molecule Inhibitor of Importin β Mediated Nuclear Import by Confocal On-Bead Screening of Tagged One-Bead One-Compound Libraries

Martin Hintersteiner, Géza Ambrus, Janna Bednenko, +8

ACS Chemical Biology

Nuclear ImportMolecular BiologySmall Molecule InhibitorAnalytical UltracentrifugationConfocal On-bead Screening +15

The chemical synthesis of oligoribonucleotides. IX. A comparison of protecting groups in the dichloridite procedure

Kelvin K. Ogilvie, Nicole Y. Thériault, Jan‐Marcus Seifert, +2

Canadian Journal of Chemistry

A ComparisonNucleic Acid ChemistryBioorganic ChemistryEngineeringBiochemistry +11

The Intranasal Application of Zanamivir and Carrageenan Is Synergistically Active against Influenza A Virus in the Murine Model

Martina Morokutti-Kurz, Marielle König‐Schuster, Christiane Koller, +9

PLoS ONE

Terminal Adenosyl Transferase Activity of Posttranscriptional Regulator HuR Revealed by Confocal On-Bead Screening

Nicole Meisner‐Kober, Martin Hintersteiner, Jan‐Marcus Seifert, +8

Journal of Molecular Biology

Signal TransductionConfocal On-bead ScreeningBiochemistryProtein ExpressionNatural Sciences +4

A Highly Potent and Cellularly Active β‐Peptidic Inhibitor of the p53/hDM2 Interaction

Martin Hintersteiner, Thierry Kimmerlin, Géraldine Garavel, +6

ChemBioChem

Peptide EngineeringCell DeathMolecular BiologyCancer BiologyTumor Biology +19

High-throughput flow injection analysis–mass spectrometry with networked delivery of colour rendered results: the characterisation of liquid chromatography fractions

Ramsay Richmond, Ekkehard Görlach, Jan‐Marcus Seifert

Journal of Chromatography A

EngineeringEnvironmental EngineeringNetworked DeliveryMedicineMass Spectrometry +7

Analysis of Protein−Small Molecule Interactions by Microscale Equilibrium Dialysis and Its Application As a Secondary Confirmation Method for on-Bead Screening

Thomas Weidemann, Jan‐Marcus Seifert, Martin Hintersteiner, +1

Journal of Combinatorial Chemistry

EngineeringMicroscale Equilibrium DialysisProtein PurificationBioanalysisBiochemical Engineering +14

Saponin Micelles Lead to High Mucosal Permeation and In Vivo Efficacy of Solubilized Budesonide

Sabine Nakowitsch, Christiane Koller, Jan‐Marcus Seifert, +13

Pharmaceutics