Single Bead Labeling Method for Combining Confocal Fluorescence On-Bead Screening and Solution Validation of Tagged One-Bead One-Compound Libraries

A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective “Ligation” of Azides and Terminal Alkynes

Vsevolod V. Rostovtsev, Luke G. Green, Valery V. Fokin et al. · Angewandte Chemie International Edition · 2002 · 11.5K citations

Natural Sciences, Chemistry, Catalysis +8

Peptidotriazoles on Solid Phase:  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides

Christian W. Tornøe, Caspar Christensen, Morten Meldal · The Journal of Organic Chemistry · 2002 · 8.5K citations

Pharmacy, Medicinal Chemistry, Catalysis +12

Generalizing the Hough transform to detect arbitrary shapes

D.H. Ballard · Pattern Recognition · 1981 · 4.4K citations

Computing, Computer Science, Mathematics +13

A new type of synthetic peptide library for identifying ligand-binding activity

Kit S. Lam, Sydney E. Salmon, Evan M. Hersh et al. · Nature · 1991 · 1.8K citations

Pharmacy, Biochemistry, Medicinal Chemistry +16

Small molecules: the missing link in the central dogma

Stuart L. Schreiber · Nature Chemical Biology · 2005 · 311 citations

Pharmacy, Chemistry, Medicinal Chemistry +13