Gilles Quéléver

Naphthyl and Coumarinyl Biarylpiperazine Derivatives as Highly Potent Human β-Secretase Inhibitors. Design, Synthesis, and Enzymatic BACE-1 and Cell Assays

Cédrik Garino, Taisuke Tomita, Nicolas Pietrancosta et al. · Journal of Medicinal Chemistry · 2006 · 59 citations · Full text

BACE-1 inhibitory activities of new substituted phenyl-piperazine coupled to various heterocycles: Chromene, coumarin and quinoline

Cédrik Garino, Nicolas Pietrancosta, Younès Laras et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 54 citations · Full text

Molecular Pharmacology, Bace-1 Inhibitory Activities, Heterocyclic +8

Synthesis of new 3-alkoxy-7-amino-4-chloro-isocoumarin derivatives as new β-amyloid peptide production inhibitors and their activities on various classes of protease

Frédéric Bihel, Gilles Quéléver, Hugues Lelouard et al. · Bioorganic & Medicinal Chemistry · 2003 · 46 citations

Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry +9

Novel cyclized Pifithrin-α p53 inactivators: synthesis and biological studies

Nicolas Pietrancosta, Flavio Maina, Rosanna Dono et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 33 citations

Pharmacology, Pifithrin-α P53 Inactivators, Anti-cancer Agent

Design of potential new HIV protease inhibitors: enantioconvergent synthesis of new pyrrolidin-3-ol, and pyrrolidin-3-one peptide conjugates

Jérôme Courcambeck, Frédéric Bihel, C. De Michelis et al. · Journal of the Chemical Society Perkin Transactions 1 · 2001 · 30 citations

Combinatorial Chemistry, Peptide Science, Chemical Biology +19