Jérôme Courcambeck

Mechanistic Basis for Reduced Viral and Enzymatic Fitness of HIV-1 Reverse Transcriptase Containing Both K65R and M184V Mutations

Jérôme Deval, Kirsten White, Michael D. Miller et al. · Journal of Biological Chemistry · 2003 · 160 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

A Loss of Viral Replicative Capacity Correlates with Altered DNA Polymerization Kinetics by the Human Immunodeficiency Virus Reverse Transcriptase Bearing the K65R and L74V Dideoxynucleoside Resistance Substitutions

Jérôme Deval, Jean‐Marc Navarro, Boulbaba Selmi et al. · Journal of Biological Chemistry · 2004 · 90 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma <i>via</i> modulation of lysosomal functions

Sonia Brun, Eloïne Bestion, Éric Raymond et al. · Autophagy · 2021 · 86 citations · Full text

Life Sciences, Oncology, Pharmacology +17

Resistance of Hepatitis C Virus to Ns3–4A Protease Inhibitors: Mechanisms of Drug Resistance Induced by R155Q, A156T, D168A and D168V Mutations

Jérôme Courcambeck, Mourad Bouzidi, R. Perbost et al. · Antiviral Therapy · 2006 · 54 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

GNS561, a new lysosomotropic small molecule, for the treatment of intrahepatic cholangiocarcinoma

Sonia Brun, Firas Bassissi, Cindy Serdjebi et al. · Investigational New Drugs · 2019 · 39 citations

Medicine, Molecular Biology, Oncology +14