Jérôme Deval

The Ambiguous Base-Pairing and High Substrate Efficiency of T-705 (Favipiravir) Ribofuranosyl 5′-Triphosphate towards Influenza A Virus Polymerase

Zhinan Jin, Lucas K. Smith, Vivek K. Rajwanshi et al. · PLoS ONE · 2013 · 273 citations · Full text

Life Sciences, Biochemistry, Infectious Diseases +15

Mechanistic Basis for Reduced Viral and Enzymatic Fitness of HIV-1 Reverse Transcriptase Containing Both K65R and M184V Mutations

Jérôme Deval, Kirsten White, Michael D. Miller et al. · Journal of Biological Chemistry · 2003 · 160 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Discovery of 4′-Chloromethyl-2′-deoxy-3′,5′-di-<i>O</i>-isobutyryl-2′-fluorocytidine (ALS-8176), A First-in-Class RSV Polymerase Inhibitor for Treatment of Human Respiratory Syncytial Virus Infection

Guangyi Wang, Jérôme Deval, Jin Tae Hong et al. · Journal of Medicinal Chemistry · 2015 · 138 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Initiation, extension, and termination of RNA synthesis by a paramyxovirus polymerase

Paul C. Jordan, Cheng Liu, Pauline Raynaud et al. · PLoS Pathogens · 2018 · 138 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

The Molecular Mechanism of Multidrug Resistance by the Q151M Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Its Suppression Using α-Boranophosphate Nucleotide Analogues

Jérôme Deval, Boulbaba Selmi, Joëlle Boretto et al. · Journal of Biological Chemistry · 2002 · 98 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8