Sheng Wu

Greatly reduced amino acid alphabets in directed evolution: making the right choice for saturation mutagenesis at homologous enzyme positions

Manfred T. Reetz, Sheng Wu · Chemical Communications · 2008 · 144 citations

Life Sciences, Molecular Biology, Molecular Evolution +4

Induced allostery in the directed evolution of an enantioselective Baeyer–Villiger monooxygenase

Sheng Wu, Juan Pablo Acevedo, Manfred T. Reetz · Proceedings of the National Academy of Sciences · 2010 · 136 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Laboratory Evolution of Robust and Enantioselective Baeyer−Villiger Monooxygenases for Asymmetric Catalysis

Manfred T. Reetz, Sheng Wu · Journal of the American Chemical Society · 2009 · 134 citations

Life Sciences, Biochemistry, Biotechnology +17

Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates

Joaquı́n Sanchis, Layla Fernández, José Daniel Carballeira et al. · Applied Microbiology and Biotechnology · 2008 · 127 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17

Characterization of a recombinant (+)-γ-lactamase from Microbacterium hydrocarbonoxydans which provides evidence that two enantiocomplementary γ-lactamases are in the strain

Jianjun Wang, Yaxin Zhu, Guogang Zhao et al. · Applied Microbiology and Biotechnology · 2014 · 22 citations

Life Sciences, Microbiology, Molecular Biology +4