Joaquı́n Sanchis

Directed Evolution of an Enantioselective Epoxide Hydrolase: Uncovering the Source of Enantioselectivity at Each Evolutionary Stage

Manfred T. Reetz, Marco Bocola, Li-Wen Wang et al. · Journal of the American Chemical Society · 2009 · 152 citations · Full text

Biosynthesis, Engineering, Biochemistry +15

A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes

Frédéric Cadet, Nicolas Fontaine, Guangyue Li et al. · Scientific Reports · 2018 · 140 citations · Full text

Improved PCR method for the creation of saturation mutagenesis libraries in directed evolution: application to difficult-to-amplify templates

Joaquı́n Sanchis, Layla Fernández, José Daniel Carballeira et al. · Applied Microbiology and Biotechnology · 2008 · 127 citations · Full text

Integrin-assisted drug delivery of nano-scaled polymer therapeutics bearing paclitaxel

Anat Eldar‐Boock, Keren Miller, Joaquı́n Sanchis et al. · Biomaterials · 2011 · 125 citations · Full text

Nanomedicine, Engineering, Polymer-drug Conjugate +5

Pervasive cooperative mutational effects on multiple catalytic enzyme traits emerge via long-range conformational dynamics

Carlos G. Acevedo‐Rocha, Aitao Li, Lorenzo D’Amore et al. · Nature Communications · 2021 · 114 citations · Full text