Nicolas Fontaine

A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes

Frédéric Cadet, Nicolas Fontaine, Guangyue Li et al. · Scientific Reports · 2018 · 142 citations · Full text

Engineering, Biotechnology, Molecular Biology +17

Machine Learning Enables Selection of Epistatic Enzyme Mutants for Stability Against Unfolding and Detrimental Aggregation

Guangyue Li, Youcai Qin, Nicolas Fontaine et al. · ChemBioChem · 2020 · 40 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

One‐shot optimization of multiple enzyme parameters: Tailoring glucose oxidase for pH and electron mediators

Raluca Ostafe, Nicolas Fontaine, David A. Frank et al. · Biotechnology and Bioengineering · 2019 · 28 citations

Engineering, Biochemistry, Biotechnology +17

Application of fourier transform and proteochemometrics principles to protein engineering

Frédéric Cadet, Nicolas Fontaine, Iyanar Vetrivel et al. · BMC Bioinformatics · 2018 · 24 citations · Full text

Life Sciences, Biochemistry, Bioinformatics +17

Flux prediction using artificial neural network (ANN) for the upper part of glycolysis

Anamya Ajjolli Nagaraja, Nicolas Fontaine, Mathieu Delsaut et al. · PLoS ONE · 2019 · 23 citations · Full text

Life Sciences, Biochemistry, Biotechnology +15