Arjan J. Groot

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool

Ragna Sannerud, Cary Esselens, Paulina Ejsmont et al. · Cell · 2016 · 284 citations · Full text

Intracellular Aβ Pool, Protein Secretion, Protein Function +10

E-Cadherin loss associated with EMT promotes radioresistance in human tumor cells

Jan Theys, Barry Jutten, R. Habets et al. · Radiotherapy and Oncology · 2011 · 218 citations

Tumor Biology, Oncology, Human Tumor Cells +9

TNF Trafficking to Human Mast Cell Granules: Mature Chain-Dependent Endocytosis

Maciej B. Olszewski, Arjan J. Groot, Jarosław Dastych et al. · The Journal of Immunology · 2007 · 153 citations · Full text

Protein Secretion, Mast Cell Disorder, Immunology +19

The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2α

Eelke Gort, Gijs van Haaften, Ingrid Verlaan et al. · Oncogene · 2007 · 128 citations

Redox Regulator, Natural Sciences, Hypoxia (Medicine) +6

COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion

Bart van de Sluis, Xicheng Mao, Yali Zhai et al. · Journal of Clinical Investigation · 2010 · 125 citations · Full text

Tumor Biology, Medicine, Tumor Growth +12