Edward J. Wawrzynczak

New coupling agents for the synthesis of immunotoxins containing a hindered disulfide bond with improved stability in vivo.

Philip E. Thorpe, Philip M. Wallace, Phillip P. Knowles et al. · PubMed · 1987 · 204 citations

Life Sciences, Immunology, Pharmacology +12

Antibody Toxin Conjugates: A Perspective

David C. Blakey, Edward J. Wawrzynczak, Philip M. Wallace et al. · Chemical immunology/Fortschritte der Allergielehre/Progress in allergy/Chemical immunology and allergy · 2015 · 67 citations

Pharmacy, Biochemistry, Immunology +11

Blood clearance in the rat of a recombinant mouse monoclonal antibody lacking the N-linked oligosaccharide side chains of the CH2 domains

Edward J. Wawrzynczak, Alan J. Cumber, Geoffrey D. Parnell et al. · Molecular Immunology · 1992 · 55 citations

Pharmacy, Biochemistry, Molecular Biology +14

Preproabrin: genomic cloning, characterisation and the expression of the A‐chain in <i>Escherichia coli</i>

K Wood, Janet M. Lord, Edward J. Wawrzynczak et al. · European Journal of Biochemistry · 1991 · 52 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Biochemical, cytotoxic and pharmacokinetic properties of an immunotoxin composed of a mouse monoclonal antibody Fib75 and the ribosome‐inactivating protein α‐sarcin from <i>Aspergillus giganteus</i>

Edward J. Wawrzynczak, Alan J. CUMBER, Geoffrey D. Parnell et al. · European Journal of Biochemistry · 1991 · 48 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +10