Hiroki Koike

Discovery and stereoselective synthesis of the novel isochroman neurokinin-1 receptor antagonist ‘CJ-17,493’

Yuji Shishido, H. Wakabayashi, Hiroki Koike et al. · Bioorganic & Medicinal Chemistry · 2008 · 64 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +9

Efficient Synthesis of [6-Chloro-2-(4-chlorobenzoyl)-1<i>H</i>-indol-3-yl]-acetic Acid, a Novel COX-2 Inhibitor

Stéphane Caron, Enrique Vázquez, Rodney W. Stevens et al. · The Journal of Organic Chemistry · 2003 · 56 citations

Medicinal Chemistry, Novel Cox-2 Inhibitor, Bioorganic Chemistry +13

Chirality Preservation of a Cation-Radical Intermediate. Tandem Oxidative Ring Expansion-Cyclization Reaction of Optically Active Bicyclo[4.1.0]heptyl Sulfides

Yoshiji Takemoto, Taiichi Ohra, Hiroki Koike et al. · The Journal of Organic Chemistry · 1994 · 30 citations

Engineering, Heterocyclic, Biochemistry +14

A diquinane synthesis using a novel cation radical-mediated intramolecular [3+2] cycloaddition of cyclopropyl sulfides

Yoshiji Takemoto, Syun‐ichirou Furuse, Hiroki Koike et al. · Tetrahedron Letters · 1995 · 24 citations

Heterocyclic, Organic Chemistry, Chemistry +5

Synthesis of 2-acylindole-3-acetic acids: a novel base-mediated indole synthesis

Kazunari Nakao, Yoshinori Murata, Hiroki Koike et al. · Tetrahedron Letters · 2003 · 19 citations

2-Acylindole-3-acetic Acids, Organic Chemistry, Chemistry +3