W. Perry Gordon

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-<i>N</i>2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-<i>N</i>4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials

Thomas H. Marsilje, Wei Pei, Bei Chen et al. · Journal of Medicinal Chemistry · 2013 · 412 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Hepatotoxicity and pulmonary toxicity of pennyroyal oil and its constituent terpenes in the mouse

W. Perry Gordon, Anthony J. Forte, Randolph J. McMurtry et al. · Toxicology and Applied Pharmacology · 1982 · 139 citations

Veterinary Medicine, Pharmacology, Toxicology +14

The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran.

W. Perry Gordon, Alain C. Huitric, C L Seth et al. · Drug Metabolism and Disposition · 1987 · 101 citations

Medicine, Pharmacology, Toxicology +16

Studies on the biotransformation in the perfused rat liver of 2-n-propyl-4-pentenoic acid, a metabolite of the antiepileptic drug valproic acid. Evidence for the formation of chemically reactive intermediates.

Albert W. Rettenmeier, K S Prickett, W. Perry Gordon et al. · Drug Metabolism and Disposition · 1985 · 85 citations

Pharmacy, Pharmacology, Toxicology +17

Genotoxicity studies with paracetamol

Erik Dybing, Jørn A. Holme, W. Perry Gordon et al. · Mutation Research/Genetic Toxicology · 1984 · 83 citations

Pharmacy, Pharmacology, Toxicology +6