Lawrence M. Refolo

Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1

Karen Duff, Chris Eckman, Cindy Zehr et al. · Nature · 1996 · 1.5K citations

Life Sciences, Neurobiology, Neuroscience +12

Nerve and epidermal growth factors induce the release of the Alzheimer Amyloid precursor from PC 12 cell cultures

Lawrence M. Refolo, Stephen R. Salton, John P. Anderson et al. · Biochemical and Biophysical Research Communications · 1989 · 132 citations

Life Sciences, Cell Biology, Neuroscience +17

Increased Aβ42(43) from cell lines expressing presenilin 1 mutations

Nitin D. Mehta, Lawrence M. Refolo, Chris Eckman et al. · Annals of Neurology · 1998 · 102 citations

Life Sciences, Genetics, Neuroscience +17

Glycosylphosphatidylinositol-anchored Proteins Play an Important Role in the Biogenesis of the Alzheimer's Amyloid β-Protein

Kumar Sambamurti, Daniel Sevlever, Thillai Koothan et al. · Journal of Biological Chemistry · 1999 · 49 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Antisense‐Induced Reduction of Presenilin 1 Expression Selectively Increases the Production of Amyloid β42 in Transfected Cells

Lawrence M. Refolo, Chris Eckman, Christian‐Mihail Prada et al. · Journal of Neurochemistry · 1999 · 45 citations

Life Sciences, Neurology, Neuroscience +17