R. H. W. M. Derksen

Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients

Ricard Cervera, Rosa Serrano, Guillermo Pons‐Estel et al. · Annals of the Rheumatic Diseases · 2014 · 962 citations · Full text

Medicine, Hematology, Clinical Epidemiology +16

Prevention of relapses in systemic lupus erythematosus

Hendrika Bootsma, Peter E. Spronk, G. de Boer et al. · The Lancet · 1995 · 292 citations

Life Sciences, Clinical Sciences, Immunology +12

Somatic mutations in the variable regions of a human IgG anti-double-stranded DNA autoantibody suggest a role for antigen in the induction of systemic lupus erythematosus.

Johan H. van Es, F H Gmelig Meyling, W R van de Akker et al. · The Journal of Experimental Medicine · 1991 · 247 citations · Full text

Life Sciences, Immunology, Molecular Genetics +17

Azathioprine/methylprednisolone versus cyclophosphamide in proliferative lupus nephritis. A randomized controlled trial

Cecile Grootscholten, G. Ligtenberg, E. Chris Hagen et al. · Kidney International · 2006 · 237 citations

Medicine, Nephrology, Pharmacotherapy +14

Lupus anticoagulant activity is frequently dependent on the presence of beta 2-glycoprotein I.

J. D. Oosting, R. H. W. M. Derksen, H. T. I. Entjes et al. · PubMed · 1992 · 175 citations

Life Sciences, Immunology, Autoimmunity +13