Hoan K. Huynh

ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii

Thomas F. Durand-Réville, Satenig Guler, Janelle Comita-Prevoir et al. · Nature Microbiology · 2017 · 271 citations

Life Sciences, Infectious Diseases, Microbiology +16

Rational design of a new antibiotic class for drug-resistant infections

Thomas F. Durand-Réville, Alita A. Miller, John P. O’Donnell et al. · Nature · 2021 · 140 citations

Life Sciences, Infectious Diseases, Medicinal Chemistry +16

Discovery of AZD9833, a Potent and Orally Bioavailable Selective Estrogen Receptor Degrader and Antagonist

James S. Scott, Amber Balazs, Bernard Barlaam et al. · Journal of Medicinal Chemistry · 2020 · 111 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Novel Bacterial NAD ⁺ -Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial Efficacy <i>In Vivo</i>

Scott D. Mills, Ann E. Eakin, Ed T. Buurman et al. · Antimicrobial Agents and Chemotherapy · 2010 · 79 citations

Life Sciences, Medicinal Chemistry, Molecular Biology +17

β-Functionalization of Saturated Aza-Heterocycles Enabled by Organic Photoredox Catalysis

Natalie Holmberg‐Douglas, Younggi Choi, Brian Aquila et al. · ACS Catalysis · 2021 · 56 citations · Full text

Natural Sciences, Chemistry, Biocatalysis +14