Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair

Yuka Nakazawa, Kensaku Sasaki, Norisato Mitsutake, +21

Nature Genetics

Genome InstabilityGenetic DisorderMedicineGeneticsMolecular Biology +4

Malfunction of Nuclease ERCC1-XPF Results in Diverse Clinical Manifestations and Causes Cockayne Syndrome, Xeroderma Pigmentosum, and Fanconi Anemia

Kazuya Kashiyama, Yuka Nakazawa, Daniela T. Pilz, +23

The American Journal of Human Genetics

Fanconi AnemiaGeneticsHematologyNuclease Ercc1-xpf ResultsPathology +3

Rhododendrol, a depigmentation‐inducing phenolic compound, exerts melanocyte cytotoxicity via a tyrosinase‐dependent mechanism

Minoru Sasaki, Masatoshi Kondo, Kohji Sato, +6

Pigment Cell & Melanoma Research

Hyaluronan Synthase 3 Regulates Hyaluronan Synthesis in Cultured Human Keratinocytes

Tetsuya Sayo, Yoshinori Sugiyama, Yoshito Takahashi, +5

Journal of Investigative Dermatology

Regenerative MedicineMedicineCutaneous BiologyHyaluronan Synthase 3Dermatology +5

Regulation of Hyaluronan (HA) Metabolism Mediated by HYBID (Hyaluronan-binding Protein Involved in HA Depolymerization, KIAA1199) and HA Synthases in Growth Factor-stimulated Fibroblasts

Aya Nagaoka, Hiroyuki Yoshida, Sachiko Nakamura, +7

Journal of Biological Chemistry

Decreased Gene Expression Responsible for Post-Ultraviolet DNA Repair Synthesis in Aging: A Possible Mechanism of Age-Related Reduction in DNA Repair Capacity

Yoshito Takahashi, Shinichi Moriwaki, Yoshinori Sugiyama, +5

Journal of Investigative Dermatology

ChromatinGenome InstabilityDna DamageAnti-agingAging +13

Autophagy Declines with Premature Skin Aging resulting in Dynamic Alterations in Skin Pigmentation and Epidermal Differentiation

Daiki Murase, Ayumi Kusaka-Kikushima, Akira Hachiya, +10

International Journal of Molecular Sciences

AgingDermatologySkin PigmentationCellular PhysiologyCell Autophagy +21

A rapid, comprehensive system for assaying DNA repair activity and cytotoxic effects of DNA-damaging reagents

Nan Jia, Yuka Nakazawa, Chaowan Guo, +6

Nature Protocols

Comprehensive SystemGenome InstabilityDna Repair ActivityDna DamageBiochemistry +11

Suppression of the responsiveness of lymphocytes from cancer patients triggered by co-culture with autologous tumor-derived cells.

Megumi Akiyama, Michael A. Bean, Kenichiro Sadamoto, +2

The Journal of Immunology

Cell TherapyImmunologySelective SuppressionCancer PatientsImmunotherapy +17

Reduction of hyaluronan and increased expression of HYBID (alias CEMIP and KIAA1199) correlate with clinical symptoms in photoaged skin

Hiroyuki Yoshida, Aya Nagaoka, Aya Komiya, +7

British Journal of Dermatology