Maria Alessandra Santucci

Identification of the first non-peptidic small molecule inhibitor of the c-Abl/14-3-3 protein–protein interactions able to drive sensitive and Imatinib-resistant leukemia cells to apoptosis

Valentina Corradi, Manuela Mancini, Fabrizio Manetti et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 78 citations

Life Sciences, Oncology, Pharmacology +15

A New Nonpeptidic Inhibitor of 14-3-3 Induces Apoptotic Cell Death in Chronic Myeloid Leukemia Sensitive or Resistant to Imatinib

Manuela Mancini, Valentina Corradi, Sara Petta et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 62 citations

Medicine, Oncology, Pharmacology +13

Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents

Marco Radi, Emmanuele Crespan, Giorgia Botta et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 57 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Computational techniques are valuable tools for the discovery of protein–protein interaction inhibitors: The 14-3-3σ case

Valentina Corradi, Manuela Mancini, Maria Alessandra Santucci et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 41 citations · Full text

Life Sciences, Medicinal Chemistry, Computational Chemistry +13

Long-term bone marrow cultures in Diamond-Blackfan anemia reveal a defect of both granulomacrophage and erythroid progenitors

Maria Alessandra Santucci, Gian Paolo Bagnara, Pierluigi Strippoli et al. · Experimental Hematology · 1999 · 39 citations · Full text

Medicine, Hematology, Pathology +16