Manuela Mancini

Molecular profiling of blastic plasmacytoid dendritic cell neoplasm reveals a unique pattern and suggests selective sensitivity to NF-kB pathway inhibition

Maria Rosaria Sapienza, Fabio Fuligni, Claudio Agostinelli et al. · Leukemia · 2014 · 175 citations · Full text

Selective Sensitivity, Unique Pattern, Immunology +8

Identification of the first non-peptidic small molecule inhibitor of the c-Abl/14-3-3 protein–protein interactions able to drive sensitive and Imatinib-resistant leukemia cells to apoptosis

Valentina Corradi, Manuela Mancini, Fabrizio Manetti et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 78 citations

Hematological Malignancy, Imatinib-resistant Leukemia Cells, Apoptosis +8

A New Nonpeptidic Inhibitor of 14-3-3 Induces Apoptotic Cell Death in Chronic Myeloid Leukemia Sensitive or Resistant to Imatinib

Manuela Mancini, Valentina Corradi, Sara Petta et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 60 citations

Next-generation sequencing for sensitive detection of <i>BCR-ABL1</i> mutations relevant to tyrosine kinase inhibitor choice in imatinib-resistant patients

Simona Soverini, Caterina De Benedittis, Kateřina Machová Poláková et al. · Oncotarget · 2016 · 58 citations · Full text

Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents

Marco Radi, Emmanuele Crespan, Giorgia Botta et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 56 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +9