Rachel Tsan

Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.

Christiane J. Bruns, Carmen C. Solórzano, Matthew T. Harbison et al. · PubMed · 2000 · 501 citations

Medicine, Oncology, Pharmacology +17

Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

Rachel Tsan, Wei‐Chien Huang, Qiuyu Wu et al. · Cancer Cell · 2008 · 487 citations · Full text

Medicine, Molecular Biology, Oncology +16

Epidermal growth factor receptor blockade with C225 plus gemcitabine results in regression of human pancreatic carcinoma growing orthotopically in nude mice by antiangiogenic mechanisms.

Christiane J. Bruns, Matthew T. Harbison, Darren W. Davis et al. · PubMed · 2000 · 422 citations

Medicine, Oncology, Pharmacology +17

Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model.

Rosa F. Hwang, Kenji Yokoi, Corazon D. Bucana et al. · PubMed · 2003 · 157 citations

Medicine, Oncology, Pharmacology +17

Blockade of Epidermal Growth Factor Receptor Signaling on Tumor Cells and Tumor-Associated Endothelial Cells for Therapy of Human Carcinomas

Cheryl H. Baker, Daniel Kedar, Marya F. McCarty et al. · American Journal Of Pathology · 2002 · 150 citations · Full text

Medicine, Cancer Biology, Oncology +17